RT Journal Article SR Electronic T1 Intractable pleural effusion in Kaposi sarcoma following antiretroviral therapy in a Caucasian female infected with HIV JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e233335 DO 10.1136/bcr-2019-233335 VO 13 IS 2 A1 Tajarernmuang, Pattraporn A1 Fiset, Pierre-Olivier A1 Routy, Jean-Pierre A1 Beaudoin, Stéphane YR 2020 UL http://casereports.bmj.com/content/13/2/e233335.abstract AB We report the case of a 57-year-old Caucasian woman with AIDS-related disseminated Kaposi sarcoma (KS) characterised by the combination of several unusual features. The chylous nature of the pleural effusions, the documented parietal pleural involvement at thoracoscopy and the marked clinical worsening through an immune reconstitution syndrome following antiretroviral therapy initiation represent several rare situations that occurred in the same female patient. In addition, the use of indwelling pleural catheters for dyspnoea palliation also represents a rare therapeutic intervention. This case is a reminder of the possibility of AIDS-related pleural KS, now uncommon in the era of antiretroviral therapy.