PT  - JOURNAL ARTICLE
AU  - Hernández Martínez, Mariola
AU  - Lizán Tudela, César
AU  - Saus Carreres, Ana
TI  - Unclassifiable lymphoma in pregnancy
AID  - 10.1136/bcr-2020-239462
DP  - 2021 Feb 01
TA  - BMJ Case Reports
PG  - e239462
VI  - 14
IP  - 2
4099  - http://casereports.bmj.com/content/14/2/e239462.short
4100  - http://casereports.bmj.com/content/14/2/e239462.full
SO  - BMJ Case Reports2021 Feb 01; 14
AB  - A 28-year-old woman, 15 weeks pregnant, consulted for cervical ache and left laterocervical mass. Imaging scans revealed a large mediastinal mass that had spread to supraclavicular and left axillar spaces, including cervicobrachial plexus. Pathological anatomy confirmed an unclassifiable lymphoma, with intermediate features between diffuse large B-cell lymphoma and classical Hodgkin’s lymphoma. CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) therapy was started with partial response. But due to disease progression, an elective caesarean section was performed (30th week of pregnancy) to begin a chemotherapy regime incompatible with pregnancy. Despite acute complications related to prematurity, the newborn could be discharged from hospital at 45 days of life. The patient did not respond to the second treatment line and she is currently undergoing a third chemotherapy regime. Given the unusual occurrence of lymphoma during pregnancy, multidisciplinary teamwork between haematologists, neonatologists and obstetricians is essential to achieve the best maternal–fetal outcome.