RT Journal Article
SR Electronic
T1 Graves’ disease associated with cholestatic jaundice and persistent diarrhoea
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e244367
DO 10.1136/bcr-2021-244367
VO 14
IS 11
A1 Rane, Siddhesh Vijay
A1 Thanage, Ravi
A1 Chandnani, Sanjay
A1 Rathi, Pravin M
YR 2021
UL http://casereports.bmj.com/content/14/11/e244367.abstract
AB Liver involvement in Graves’ disease can be seen as a part of autoimmune process or rarely, due to the direct effects of thyrotoxicosis on liver. Hyperthyroidism can also have gastrointestinal manifestations like frequent bowel movements, diarrhoea, even malabsorption with steatorrhoea. We report a 36-year-old man with hyperthyroidism, presenting with cholestatic jaundice and persistent small bowel diarrhoea. He was diagnosed to have Graves’ disease and after ruling out more common causes, the cause of cholestatic jaundice was supposed to be Graves’ disease. Considering this possibility, the patient was started on treatment with carbimazole. As patient’s thyroid function tests started improving, he showed significant clinical and biochemical improvement from liver point of view as well.