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Case of Kikuchi-Fujimoto disease associated with multiple myeloma
  1. Luqman Safwan Fauzi1,
  2. Vidhi Unadkat1,
  3. Siti Nadhirah Binti Abd Hadi2 and
  4. Ciro Rinaldi2
  1. 1Internal Medicine, Pilgrim Hospital, Boston, Lincolnshire, UK
  2. 2Department of Haematology, Pilgrim Hospital, Boston, Lincolnshire, UK
  1. Correspondence to Dr Luqman Safwan Fauzi; luqman.fauzi{at}doctors.org.uk

Abstract

We present a 47-year-old, South-African origin, woman with a background of stable monoclonal gammopathy of unknown significance (MGUS) who attended A&E with a history of coryzal symptoms associated with persistent fever, lymphadenopathy and a new onset of rash, not responding to antibiotics and paracetamol. A trial of high-dose steroids resolved symptoms. Bone marrow biopsy confirmed a progression of MGUS into multiple myeloma and her axillary lymph node biopsy analysis supported a diagnosis of Kikuchi-Fujimoto disease (KFD). This is an unusual presentation where KFD has been noted alongside MGUS progression to multiple myeloma. Haematology follow-up is underway.

  • medical management
  • pathology
  • monoclonal gammopathy of undetermined significance associated neuropathy
  • malignant and benign haematology

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Footnotes

  • Contributors LSF, VU and SNBAH have contributed to writing, researching and editing of this manuscript. CR has provided guidance on the manuscript write-up.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.