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Case Reports: Rare disease
Carcinoid heart disease: a potentially fatal complication of carcinoid syndrome
  1. Mustafa Bdiwi1,
  2. Karthik Ramaseshan1,
  3. Mohammed Uddin2,
  4. Mishita Goel2,
  5. Saman Razzaq1,
  6. Mohamed Alrayyashi1 and
  7. Luis Afonso2
  1. 1Department of Internal Medicine, Wayne State University/ Detroit Medical Center, Detroit, Michigan, USA
  2. 2Cardiology/Department of Internal medicine, Wayne State University/ Detroit Medical Center, Detroit, Michigan, USA
  1. Correspondence to Dr Mustafa Bdiwi; mbdiwi{at}med.wayne.edu

Abstract

Carcinoid heart disease is a unique and serious cardiac complication of the neuroendocrine tumour that affects the right side of the heart, especially the tricuspid and pulmonic valves, eventually causing right heart failure. We present a middle-aged man with a history of well-differentiated neuroendocrine tumours of the small intestine with extensive metastases to the liver, mesentery and spine who is receiving monthly octreotide therapy. He presented with generalised fatigue, severe ascites and worsening dyspnoea. Both the transthoracic echocardiography and transoesophageal echocardiography revealed severe tricuspid and pulmonic regurgitations. He was considered a poor surgical candidate, underwent transcatheter pulmonic valve replacement with two bioprosthetic valve-in-valve implantations and was discharged in a stable condition.

  • Valvar diseases
  • Interventional cardiology

https://doi.org/10.1136/bcr-2023-255518

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    Footnotes

    • Twitter @mustafahbdiwi

    • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms and critical revision for important intellectual content: MB, KR, MU, MG, SR, MA and LA. The following authors gave final approval of the manuscript: MB.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.