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Critical care
Hyperkaliaemic cardiac arrest in Angelman’s syndrome following suxamethonium
  1. Dylan Whitaker,
  2. Heba Yousef and
  3. Augusto Mauro
  1. Critical Care, North West Anglia NHS Foundation Trust, Peterborough, UK
  1. Correspondence to Dr Dylan Whitaker; dylan.whitaker1@nhs.net

Abstract

We present a case of hyperkaliaemic cardiac arrest in a patient with Angelman’s syndrome after administration of suxamethonium in rapid sequence intubation. The patient was admitted to the critical care unit in with aspiration pneumonia and intestinal obstruction. They had a cardiac arrest after suxamethonium administration. Potassium level was remarkably high (11.1 mmol/L). ROSC was achieved after 26 min of CPR and resuscitation. We discuss Angelman’s syndrome molecular pathology, especially affecting the potassium channels transmission and its relation to suxamethonium in emergency intubation.

  • Anaesthesia
  • Arrhythmias
  • Contraindications and precautions
  • Resuscitation
  • Genetics

https://doi.org/10.1136/bcr-2024-261589

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    Footnotes

    • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: All authors (DW, HY and AM). The following authors gave final approval of the manuscript: All authors (DW, HY and AM). AM is the guarantor.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.