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Vitamin B12 deficiency presenting as neck pain and cervical radiculopathy
  1. Ashin Mehta1,
  2. Whitney Lynch2 and
  3. Pinky Jha2
  1. 1Medical School, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
  2. 2Internal Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
  1. Correspondence to Ashin Mehta; amehta{at}mcw.edu

Abstract

Vitamin B12 is required for the formation of haematopoietic cells and the synthesis of myelin. Deficiency typically presents with fatigue and megaloblastic anaemia. Prolonged deficiency can cause neurological symptoms such as paresthesia, which can progress to subacute combined degeneration of the spinal cord. We describe an unusual presentation of B12 deficiency in a young man who was initially diagnosed and treated for cervical radiculopathy. This case highlights the challenges of diagnosing B12 deficiency in patients with neurologic but without haematologic, abnormalities. While the current incidence of B12 deficiency in developed countries is low, cases are likely to rise with the increased adoption of veganism. Clinicians should be aware of the variable presentations of B12 deficiency because delayed diagnosis and treatment increases morbidity and can cause irreversible neurological deficits.

  • Vitamins and supplements
  • Malnutrition

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Footnotes

  • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: AM (Patient), WL and PJ. The following authors gave final approval of the manuscript: AM, WL and PJ.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.