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Critical care
Role of ulinastatin in steroid-induced pancreatitis
  1. Devarakonda Prithvi,
  2. Neeraj Kumar,
  3. Ajeet Kumar and
  4. Abhyuday Kumar
  1. Anaesthesiology and Critical Care, AIIMS, Patna, India
  1. Correspondence to Dr Neeraj Kumar; neeraj.jlnmc{at}gmail.com

Abstract

Steroid-induced acute pancreatitis is a rare form of pancreatitis that requires intensive care and has a high morbidity and mortality rate as there is no specific treatment. Management of steroid-induced pancreatitis is generally non-specific and supportive. Here, we are presenting a man in his 40s presented with epigastric pain, fever and vomiting. The patient was diagnosed case of rheumatoid arthritis, for which he was receiving regular 5 mg oral prednisolone therapy. Based on history, and clinical, biochemical and radiological imaging a diagnosis of steroid-induced pancreatitis was made, which was successfully managed with the help of ulinastatin and other supportive treatments. A serine protease inhibitor like ulinastatin may be used early in the clinical management of steroid-induced pancreatitis.

  • Liver disease
  • Pancreatitis
  • Intensive care
  • Medical management

https://doi.org/10.1136/bcr-2024-260019

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    Footnotes

    • X @drneeraj_aiimsp

    • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: NK and DP. Drafting of the text: NK and DP. For sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms: NK, DP, AjK and AbK. Critical revision for important intellectual content. The following authors gave final approval of the manuscript: DP, NK, AbK and AjK.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.