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Dentistry and oral medicine
Rare mandibular condition presenting as trismus: an exploration of IgG4-related disease
  1. Jitendra Chawla1,
  2. Poongodi Rajagopal2,
  3. Navaneeth Yerragudi1 and
  4. JS Anuvindha1
  1. 1 Dentistry, AIIMS Mangalagiri, Mangalagiri, Andhra Pradesh, India
  2. 2 Pathology, AIIMS Mangalagiri, Mangalagiri, Andhra Pradesh, India
  1. Correspondence to Dr Jitendra Chawla; jitendra.dental{at}aiimsmangalagiri.edu.in

Abstract

A woman in her 30s presented with a 12-month history of reduced mouth opening and swelling on the right side of her mandible. The swelling was non-tender and firm on palpation. The swelling began to increase in size after the extraction of her carious wisdom tooth. Histopathological and serological examinations confirmed the diagnosis of IgG4-related disease, manifested as a mass in the mandible. The patient was prescribed oral corticosteroids at a tapering dosage over 8 weeks. After 3 months, there was an improvement in the patient’s mouth opening and a reduction in the size of the swelling. The patient remains in follow-up care. Including IgG4-related disease in the list of potential diagnoses for oral soft tissue masses is crucial, given their positive response to medical treatment, highlighting the significance of an accurate diagnosis to prevent unnecessary surgery, with oral lesions potentially serving as early indicators before multiorgan complications arise.

  • Immunohistochemistry
  • Dentistry and oral medicine
  • Rheumatology

https://doi.org/10.1136/bcr-2024-260749

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    Footnotes

    • X @DrNavaneeth

    • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: JSA, JC and PR. The following authors gave final approval of the manuscript: JC.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.