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Psychiatry
Zuclopenthixol decanoate induced dysphagia
  1. Olivia Dupere1,
  2. Haeun Ji2 and
  3. Lisa Williams3
  1. 1Mersey and West Lancashire Teaching Hospitals NHS Trust, Southport, UK
  2. 2Wirral University Teaching Hospital NHS Foundation Trust, Upton, UK
  3. 3Mersey Care NHS Foundation Trust, Southport, UK
  1. Correspondence to Dr Olivia Dupere; olivia.dupere{at}doctors.org.uk

Abstract

Dysphagia, a well-recognised adverse effect in many different antipsychotics, is not a formally acknowledged side effect in zuclopenthixol. This case report describes a patient with known bipolar affective disorder who had been recently stabilised on zuclopenthixol decanoate and presented with sudden onset severe oropharyngeal dysphagia. Symptoms spontaneously resolved with the discontinuation of the medication, and this report explores the suggested underlying mechanisms from literature.

  • Psychiatry (drugs and medicines)
  • Neurogastroenterology
  • Parenteral / enteral feeding
  • Unwanted effects / adverse reactions
  • Psychiatry of old age

https://doi.org/10.1136/bcr-2025-265171

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    Footnotes

    • Contributors The report was created with equal contribution from OD and HJ, with support and guidance from consultant LW. LW is the guarantor for this report.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.