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Immunology
RSV-induced infantile haemorrhagic oedema (Finkelstein–Seidlmayer vasculitis)
  1. Selin Arslan1,
  2. Melik Berke Tuncel1,
  3. Ece Tüsüz Önata2 and
  4. Öner Özdemir2
  1. 1Sakarya University Medical Faculty, Adapazarı, Sakarya, Turkey
  2. 2Department of Pediatrics, Division of Allergy and Immunology, Sakarya University Medical Faculty, Adapazarı, Sakarya, Turkey
  1. Correspondence to Professor Öner Özdemir; oner.ozdemir.md{at}gmail.com

Abstract

Acute infantile haemorrhagic oedema (AIHE, Finkelstein–Seidlmayer vasculitis) is a leucocytoclastic vasculitis involving small vessels confined to the skin in infants aged 6–24 months. The disease is a benign condition with a dramatic onset characterised by inflammatory oedema in the target or cocard pattern, and ecchymotic purpura in a well (non-toxic) appearing child. It resolves completely spontaneously within 1–3 weeks. Although viral infections have been blamed in the aetiology of AIHE, to our knowledge, there is no reported case of AIHE after respiratory syncytial virus (RSV). In this article, we describe an infant boy with rosette-shaped purpuric skin lesions on the face, trunk and limbs, clinically consistent with the diagnosis of AIHE, with symptoms of upper respiratory tract infection and laboratory investigations revealed RSV infection.

  • Immunological products and vaccines
  • Infections

https://doi.org/10.1136/bcr-2025-265686

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    Footnotes

    • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: SA, MBT, ETÖ, ÖÖ. The following authors gave final approval of the manuscript: SA, MBT, ETÖ, ÖÖ. ÖÖ is the guarantor.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.