You are here

Article Text

Article menu
Download PDFPDF
Unexpected outcome (positive or negative) including adverse drug reactions
CASE REPORT
Dulaglutide-induced cerebral venous thrombosis in a patient with type 2 diabetes mellitus
  1. Rajesh Rajput1,
  2. Vaibhav Pathak1,
  3. Pawan Kumar Yadav1,2,
  4. Sanat Mishra1
  1. 1Department of Endocrinology and Medicine Unit V, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
  2. 2Department of Medicine, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
  1. Correspondence to Dr Rajesh Rajput, drrajeshrajput{at}outlook.com

Summary

Though patients with diabetes mellitus are at a high risk of atherothrombotic events, every such event should not be attributed to the disease itself. We present a case of a patient with diabetes with headache and blurring of vision for 3 days. Brain imaging revealed right transverse sinus thrombosis and acute infarct of the right posterior parieto-occipital region, predominantly in the posterior cortical watershed zone. The patient was on subcutaneous dulaglutide for 3 weeks and was having nausea and vomiting. Various causes of cerebral venous thrombosis were ruled out with appropriate laboratory investigations. Finally, cerebral venous thrombosis was attributed to dulaglutide-induced nausea and vomiting which led to severe dehydration.

  • diabetes
  • stroke

https://doi.org/10.1136/bcr-2018-226346

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes

    • Contributors RR is the guide and mentor under whose guidance this group is managing patients. New thought and curiosity are imbibed each time a patient is admitted for management. VP is senior resident who supervised the progress in the management of the patient and gave his inputs from time to time. PKY managed the patient and ensured that treatment is delivered on time and in proper form. SM helped in getting investigations done on time and ensured that these are least bothersome to the patient. We worked as a team and ensured that patient got the best possible treatment at lower cost.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.